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    Curriculum Vitae

    Hong-Fang Ji

    female, Assoc. Professor, Ph.D. Graduated from Johannes Kepler University of Linz in Austria with Doctor Degree of Science. Research interest focuses on protein Structure-Activity Relationships and Computer-Aided Drug Design. Having published about 60 SCI papers in high-level international journals, such as Trends Biochem. Sci. (IF: 14.99), EMBO. Rep. (IF: 7.45), Genome Biol. (IF: 6.59) and BioEssays (IF: 5.40).

    Representative Publications£º

    1£®Hong-Fang Ji, Hong-Yu Zhang, Ling-Ling Chen. Why are prion diseases precluded by non-mammals? Trends Biochem. Sci. 2007, 32: 206-208.

    2£®Hong-Fang Ji, De-Xin Kong, Liang Shen, Ling-Ling Chen, Bin-Guang Ma, Hong-Yu Zhang. Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery. Genome Biol. 2007, 8: R176.

    3£®Hong-Fang Ji, Xue-Juan Li, Hong-Yu Zhang, Natural products and drug discovery. EMBO Rep. 2009, 10: 194-200.

    4£®Hong-Fang Ji, Lei Chen, Hong-Yu Zhang, Organic cofactors participated more frequently than transition metals in redox reactions of primitive proteins. BioEssays 2008, 30: 766-771.

    5£®Liang Shen, Hong-Fang Ji, Hong-Yu Zhang, Why is the C-terminus of A¦Â(1-42) more unfolded than that of A¦Â(1-40)? Clues from hydrophobic interaction. J. Phys. Chem. B 2008, 112: 3164-3167.

    6£®Hong-Fang Ji, Liang Shen, Rita Grandori, Norbert M¨¹ller. The effect of heme on the conformational stability of micro-myoglobin. FEBS J. 2008, 275: 89-96.

    7£®Hong-Fang Ji, Hong-Yu Zhang. A theoretical study on Cu(II)-Binding modes and antioxidant activity of mammalian normal prion protein. Chem. Res. Toxicol. 2004, 17: 471-475.

    8£®Hong-Fang Ji, Hong-Yu Zhang. A comparative molecular dynamics study on thermostability of human and chicken prion proteins. Biochem. Biophys. Res. Commun. 2007, 359: 790-794.

    9£®Hong-Fang Ji, Liang Shen, Hong-Yu Zhang. ¦Â-Lactam antibiotics are multipotent agents to combat neurological diseases. Biochem. Biophys. Res. Commun. 2005, 333: 661-663.

    10£®Hong-Fang Ji, Hong-Yu Zhang. A new strategy to combat Alzheimer's disease. Combining radical-scavenging potential with metal-protein-attenuating ability in one molecule. Bioorg. Med. Chem. Lett. 2005, 15: 21-24.